The Genome of Craig Venter September 4, 2007
Posted by Bertalan Meskó in Genome, Medicine, Personalized medicine, genetics, science.trackback
Yes, it was published today at PLoS Biology:
The Diploid Genome Sequence of an Individual Human
We have generated an independently assembled diploid human genomic DNA sequence from both chromosomes of a single individual (J. Craig Venter)… Comparison with previous reference human genome sequences, which were composites comprising multiple humans, revealed that the majority of genomic alterations are the well-studied class of variants based on single nucleotides (SNPs)… The existence of a well-characterized diploid human genome sequence provides a starting point for future individual genome comparisons and enables the emerging era of individualized genomic information.
He carries
- a gene variant linked to moist ear wax production
- genes linked to both heart disease (SORL1) and longevity
- genes linked to Alzheimer’s (APOE)
- macular degeneration
- high cholesterol
- carries up to seven gene types linked to tobacco addiction
“We don’t need to fear our genetic codes,” he said.
I have to agree absolutely with it!
Now I have to go to the lab, but tonight, I’m going to take a deeper look at this article…
Until then, here are some links for your pleasure:
- How one scientist became the experiment (Globeadnmail.com)
- First individual genome sequence published (Biology News Net)
- Finding said to show “race isn’t real” scrapped (Science World)
- All about Craig: the first ‘full’ genome sequence (Nature News)
I don’t fear genetic code — I fear what we’ll do with the information and the ability to alter it. Aside from abuses, which is a major consideration, of course, I am concerned about the descent into comfortable mediocrity. More often than not, the greatest accomplishments have come from those with something to overcome.
So exciting research on the one hand, but scary on the other.
One more step on the road to find the billion dollar genome…
“what we’ll do with the information and the ability to alter it”
Absolutely! That’s the most important point. When people will get their genetic code (totally sequenced) they will also get an incredible amount of information. We’ll have to teach them how to use that…
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