Comments on: Navigenics, 23andMe and Helix Health: The Review http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/ A doctor's journey in genetics PhD and medicine through web 2.0 Tue, 14 Feb 2012 15:32:10 +0000 hourly 1 http://wordpress.com/ By: 23andMe Now Offers Sequencing for $999 « ScienceRoll http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-88172 Sun, 02 Oct 2011 09:27:56 +0000 http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-88172 [...] ago, I wrote about how 23andMe analyzed someone’s genes for $999 (only a few gene variations were used for [...]

]]> By: A living, breathing, test tube | A human's experiment, one science day at a time http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-80635 Thu, 12 May 2011 18:49:37 +0000 http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-80635 [...] of this service, but I’ve watched the price go down over the years, read extensively the reviews comparing different genetic testing services, become less worried about the security of my personal genetic material (and used a pseudonym when [...]

]]> By: blackburn takeaways http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-72624 Sun, 21 Nov 2010 00:59:09 +0000 http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-72624 interesting comments and post…

]]> By: Earl T Dumitru, PhD http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-43311 Tue, 05 May 2009 15:56:12 +0000 http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-43311 Now is May 5,2009, and Sergy Brin (23andME.com) is collecting 10,000 Parkinsons Patients (PD) in a data-base, intended for “bottoms-up analysis. There is an overlap of Clinical definitions with Alzheimers (ALZ) and PD There is very litle overlap at the research level, and funding for research is captive to this specialization. Prof Larry Goldstein of UCSan Diego maay have some comments if asked .

]]> By: The Mission of Navigenics: Interview « ScienceRoll http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-35012 Thu, 01 May 2008 18:16:40 +0000 http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-35012 [...] Navigenics, 23andMe and Helix Health: The Review [...]

]]> By: 23andme extracts your gene code - are you ready to face the results? « Atentia’s Weblog http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-33676 Thu, 24 Jan 2008 02:58:35 +0000 http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-33676 [...] Comparison of companies offering DNA encoding service. If you’re thinking about it, have a look here. [...]

]]> By: Personal Genome Explorer at Home: How to analyze the results of your genome? « ScienceRoll http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-33629 Mon, 21 Jan 2008 23:22:37 +0000 http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-33629 [...] Navigenics, 23andMe and Helix Health: The Review [...]

]]> By: tom http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-31010 Thu, 20 Dec 2007 23:30:51 +0000 http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-31010 you’re amazingly hot. what’s your preference: M, F or M+F

]]> By: Michelle Kelleher http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-30896 Wed, 19 Dec 2007 21:14:44 +0000 http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-30896 Assuming Navigenics are using standard Affymetrix arrays, which I would guess they are, on Affymetrix’s website you can log into an application called NetAffx which gives searchable annotation information for the SNP’s they screen – including mapping information and external links to other sites

http://www.affymetrix.com/support/help/genotyping_glossary/index.affx

I haven’t worked for Affymetrix for several years but as far as I know after registering anyone can still use NetAffx for free. I’m assuming Navigenics will utilize all this information but will only provide information on SNP’s scientifically correlated with disease. Also don’t forget that SNP’s are primarily used to map genes associated with illness and are most likely not located in actual genes so additional tests and probably sequencing will probably be required.

]]> By: Bio::Blogs #17 - The one Santa brough us http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-29362 Sun, 02 Dec 2007 03:28:34 +0000 http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-29362 [...] he is not the only one posting about [...]

]]> By: Knome: The Review « ScienceRoll http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-29177 Thu, 29 Nov 2007 23:18:50 +0000 http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-29177 [...] Knome: The Review November 30, 2007 Posted by Bertalan Meskó in 1000$ Genome, 23andMe, Genetic testing, Genome, Health 2.0, Invention, Personalized medicine, Policy and Law, Prevention, genetics, science. trackback As today is the day when Knome launches the first commercial whole-genome sequencing and analysis service for individuals, I thought it’s time to write the review about them. If you want to read the review about 23andMe, Navigenics or Helix Health, check out this post. [...]

]]> By: A Round-Up of Discussions Following the Launch of deCODEme and 23andMe » The Genetic Genealogist http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-28486 Wed, 21 Nov 2007 07:02:10 +0000 http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-28486 [...] Meskó at Scienceroll recently rated the websites of Navigenics, Helix Health, and 23andMe. Since 23andMe’s website was redesigned as [...]

]]> By: Gene Genie #20 | The Molecular Biology Blog http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-28291 Mon, 19 Nov 2007 00:06:03 +0000 http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-28291 [...] Gene Genie founder and Scienceroll writer Berci Mesko reviewed the websites of the three major personalized genetics companies in Navigenics, 23andMe and Helix Health: The Review, [...]

]]> By: 23andMe: The Re-Review « ScienceRoll http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-28245 Sun, 18 Nov 2007 12:22:06 +0000 http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-28245 [...] Policy and Law, Prevention, Technology, Video, genetics, science. trackback A week ago, I wrote a review about the three major companies focusing on personalized genetics. That time, I couldn’t include all the required information [...]

]]> By: Bertalan Meskó http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-27800 Tue, 13 Nov 2007 07:40:28 +0000 http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-27800 Thank you for the valuable comments! I’m going to write more reviews as I get more and more requests and there are plenty of companies to cover. Stay tuned!

]]> By: Barb http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-27749 Mon, 12 Nov 2007 22:14:40 +0000 http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-27749 Navigenics is the only site that tells you their testing laboratory has CLIA certification which is essential for clinical laboratories and tells the consumer – physician or patient – that the lab meets high criteria for quality testing. Research labs rarely meet these standards of operation. Caveat emptor…….

]]> By: Zsolt Harsanyi, Ph.D. http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-27735 Mon, 12 Nov 2007 19:28:53 +0000 http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-27735 Dear Bertalan,
In 1981 I authored a book, Genetic Prophecy: Beyond the Double Helix, developing the concept of predictive medicine. At that time, we didn’t have hundreds of SNP’s that could be correlated with clinical outcomes. We only had a number of biological markers, such as HLA and blood group antigens, and enzyme variants that were, of course, products of genes. The problem then, as it is now, lies in the practical consequences of knowing who is likely to develop a medical condition. I would judge each of the companies you reviewed on the usefulness of the information they provide to the individual, whether it is based on genes, proteins, or even physiological parameters.
Keep probing.

]]> By: Ethel Rubin, PhD http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-27732 Mon, 12 Nov 2007 19:03:44 +0000 http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-27732 Bertalan,
I like your review, but am all too aware that research has a long way to go to get to the point of personal genomics and truly personalized medicine. Our biomedical informatics company is helping such translational research: http://www.biofortis.com.

A molecular oncologist by training, I get a lot of questions regarding disease predispositions for which there is no intervention currently available. Some of these companies will clearly stay away from such controversy. Such biomedical ethics dillemas will need to play out in the genetics arena. Personally, I’d rather know (and have the opportunity to plan) than not know, but there are lots of people that feel the opposite. We are all interested in seeing how commercially successful these new personalized genomics companies will be!

]]> By: PersonalGnome http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-27724 Mon, 12 Nov 2007 17:53:18 +0000 http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-27724 Bertalan, nice side-by-side comparison. Have you considered adding http://www.biophysicalcorp.com/ into the collection of companies? I realize they work at the protein level (predictive biomarkers) rather than genomic level, the goal seems to be the same: predicting your future personal health and providing health guidance based on the predictions. Acutally, it would be interesting to hear your thoughts on the reliability of genome-based vs proteome-based health predictions. Thanks.

]]> By: The Genetic Genealogist » Navigenics - A Personal Genomics Start-Up http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-27685 Mon, 12 Nov 2007 07:01:59 +0000 http://scienceroll.com/2007/11/10/navigenics-23andme-and-helix-health-the-review/#comment-27685 [...] has an interesting round-up of Navigenics, 23andMe, and Helix Health. He reviews their websites and their (proposed) services, [...]

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