Is IT ready for the Dreaded DNA Data Deluge? November 5, 2008
Posted by Dr. Bertalan Meskó in genetics, Google, Video.trackback
Here is a recent presentation of the Google Tech Talks series. The speaker is Dr. Andras Pellionisz (also from JunkDNA.com) and the topic:
Is “Big IT” ready for the avalanche of data, to be obtained and processed e.g. while the patient is still on the operating table, to be diagnosed, and how the genomics glitch, that caused a benign or malign tumor, could be compensated for?
Algorithmic approaches are needed to better understand genome regulation, even for the simple reason to deploy most effective data retrieval, data storage and computational means, via both parallel hardware and software, but more importantly for opening entirely new perspectives.
Scientists more interested in peer-reviewed science journal publication may wish to look up “The Principle of Recursive Genome Function” (free full text is available here. The point that some still miss in lesser blogs is that the Principle of Recursion not merely reverses two obsolete dogmas that hindered genomics for over half a Century, but surpasses them by a mathematical (fractal geometrical) algorithmic approach. Software-enabling theoretical frameworks are essential in emerging personal genomics, since genomics became a chapter in informatics, and thus information technology could only help by the default (“brute force”) computation, that is usually prohibitively expensive – unless nifty algorithms identify the intrinsic mathematics of genome function and thus reduce the problem. For instance, the rapidly dropping price of full genome sequences enables any/all kinds of searches – but first we must program what the IT system should search for.
pellionisz_at_junkdna.com