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MicroRNA and personalized medicine?

Barbara Duck from The Medical Quack blog shared a link with me yesterday and I was surprised to see how strong the connection is between personalized medicine and the world of microRNAs. MicroRNAs (miRNA) are single-stranded RNA molecules of about 21–23 nucleotides in length, which regulate gene expression; according to Wikipedia.

The link took me to the website of Rosetta Genomics, a company that was founded in Israel in 2000. From the FAQ:

Rosetta Genomics mission is to develop a novel class of diagnostics and therapeutics based on a recently discovered family of genes called microRNAs.

Rosetta Genomics is developing diagnostic and therapeutic products based on micro-ribonucleic acid, commonly known as microRNA, primarily for cancer and women’s health indications.

rosetta-genomics

They provide 3 diagnostic tests:

  • miRview Squamous: differentiates squamous from non-squamous non-small cell lung cancer
  • miRview  mets: dentifies the tissue-of-origin of metastatic tumors.
  • miRview  meso: differentiates malignant pleural mesothelioma from peripheral adenocarcinomas of the lung or metastatic carcinomas involving the lung pleura.

It will be interesting to see how they move forward with this concept.

And in case you need a miRNA search engine, here is Intragenic miRNA browser:

mirna-search

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