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Posts from the ‘About me’ Category

Success Stories in Empty Shop Windows

I was invited to present my story with Webicina.com in a project organized by Design Terminal. They cover the windows of empty shops with posters describing success startup stories in the streets of Budapest. Here is mine. Social media sometimes meets real life opportunities.

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My Open Access Success Story

An interview with me focusing on how open access changed the way I conduct my research in genomics was published on Open Access Success Stories. An excerpt:

So what happened when he published his first paper? Naturally, Dr Mesko chose to publish it in an open access journal and to use his expertise with social media to share it as widely as possible.

“As I’ve been a medical blogger for years, it was clear to me I would like to get as much feedback as possible for my work so we decided to publish the paper in an open access journal. I wanted to get suggestions, I wanted to hear the opinion of respected scientists, some of whom were also bloggers,” explains Dr Mesko.

Managing the Social Media Presence of a Popular Health Portal

I’ve been working on projects related to health and social media for years. I’ve been a consultant to health 2.0 and pharma companies, have been managing two award winning blogs (in English and Hungarian) and launched Webicina.com, the first free social media curation service. I’ve always wanted to use this experience and expertise and manage the social media presence of the biggest health portal in Hungary, HaziPatika.com that has over 2,5 million visits a month.

It’s a great pleasure to announce that I’m now managing the Facebook, Twitter and blog channels of HaziPatika.com, the biggest, most popular health portal that has been serving the community since 1999! I’m also a consultant now regarding the total online and digital communication of the site. Though this is a Hungarian project, I’ll keep you updated about how a properly managed and designed social media presence can boost the image of a major national health portal.

Until then, see you also on the official blog or the Facebook and Twitter channel of HaziPatika.com.

Being a co-author of a medical textbook: Medical Communication

I had the honour to write a chapter for a new medical textbook focusing on Medical Communication. My chapter is about medical communication, online tools, telemedicine, using e-mails between patients and doctors, virtual worlds, mobile applications and more.

The textbook is available in English and German and will be used at medical universities.

Webicina Featured by the Kairos Society

A few days ago, I took part in the Kairos Global Summit in New York; attended presentations from the great Thomas Goetz, Peter Diamandis and Danial Kraft, among others at the United Nations HQ. I also had a chance to exhibit Webicina.com, my free service that curates medical social media resources for medical professionals and e-patients, at the New York Stock Exchange. I thought I would share a few images with you.

The Kairos Society is an international student-run not-for-profit foundation based in the United States. We started with the belief that the key to improving our world lies in uniting the next generation of leaders to develop globally impactful innovations. To this end, Kairos has built a member base consisting of some of the brightest students from top universities around the world. Along with guidance from some of today’s foremost leaders, these students are working together to use entrepreneurship and innovation.

Times Square

 

At the United Nations HQ

 

Exhibiting Webicina.com at the New York Stock Exchange

 

Nobel Peace Prize given to UN in 2001

 

New York Stock Exchange

 

First Step in a PhD: Peripheral Blood Genomics

After graduating from medical school last year, I started PhD in the field of clinical genomics in October of 2009. My first paper (Peripheral blood gene expression patterns discriminate among chronic inflammatory diseases and healthy controls and identify novel targets) just came out in BMC Medical Genomics. Publishing our results in an open access journal was a real priority for me. The provisional pdf is now available. The hardest task was to visualize the findings.

Your comments, as always, are most welcome!

Background

Chronic inflammatory diseases including inflammatory bowel disease (IBD; Crohn’s disease and ulcerative colitis), psoriasis and rheumatoid arthritis (RA) afflict millions of people worldwide, but their pathogenesis is still not well understood. It is also not well known if distinct changes in gene expression characterize these diseases and if these patterns can discriminate between diseased and control patients and/or stratify the disease. The main focus of our work was the identification of novel markers that overlap among the 3 diseases or discriminate them from each other.

Methods

Diseased (n=13, n=15 and n=12 in IBD, psoriasis and RA respectively) and healthy patients (n=18) were recruited based on strict inclusion and exclusion criteria; peripheral blood samples were collected by clinicians (30 ml) in Venous Blood Vacuum Collection Tubes containing EDTA and peripheral blood mononuclear cells were separated by Ficoll gradient centrifugation. RNA was extracted using Trizol reagent. Gene expression data was obtained using TaqMan Low Density Array (TLDA) containing 96 genes that were selected by an algorithm and the statistical analyses were performed in Prism by using non-parametric Mann-Whitney U test (P-values < 0.05).

Results

Here we show that using a panel of 96 disease associated genes and measuring mRNA expression levels in peripheral blood derived mononuclear cells; we could identify disease-specific gene panels that separate each disease from healthy controls. In addition, a panel of five genes such as ADM, AQP9, CXCL2, IL10 and NAMPT discriminates between all samples from patients with chronic inflammation and healthy controls. We also found genes that stratify the diseases and separate different subtypes or different states of prognosis in each condition.

Conclusions

These findings and the identification of five universal markers of chronic inflammation suggest that these diseases have a common background in pathomechanism, but still can be separated by peripheral blood gene expression. Importantly, the identified genes can be associated with overlapping biological processes including changed inflammatory response. Gene panels based on such markers can play a major role in the development of personalized medicine, in monitoring disease progression and can lead to the identification of new potential drug targets in chronic inflammation.

2 Conferences and 3 Days in Berlin

I just got back from Berlin after 3 productive days and 2 conferences. On the 29th and 30th of March, I attended the Digital Pharma Europe and also gave a presentation about the physician’s perspective. The Twitter community was quite active under the hashtag #digpharm, here is the transcript of the numerous messages in PDF. And Mark Senak did an interview with me.

On the 31st of March, I attended the Healthcare Social Media EU Camp which was a real unconference with amazing discussions. The whole day was archived through Ustream and Twitter under the hashtag #hcsmeucamp.

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